Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA.

Nat Commun · 2024 · PMC11615295 · PMID 39627229

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showed a trendno p-value reported

Consistently, IHC showed a trend of higher SPINT1 levels in pancreas islets of prediabetic individuals (HbA1c between 5.7 and 6.4%) compared to non-diabetic ones (Supplementary Fig. 9b ).

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