Quantitative pharmacodynamics functional evaluation of Chinese medicine Qizhu formula in mice with dynamic near-infrared photoacoustic imaging.

At the same time, the three QZ groups showed an advantage over the positive group, and the three dose groups of QZ granules showed a trend of dose-response relationship in some individual parameters.

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Immunofluorescence staining results showed that MMP-2 decreased while Col-I increased in the model group; in contrast, in the four treatment groups, the expression of MMP-2 showed an increasing trend, while Col-I significantly decreased ( Fig. 1 B).

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