Chemically Defined Organoid Culture System for Cholangiocyte Differentiation.

Adv Healthc Mater · 2024 · PMC11616262 · PMID 39044566

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As shown in Figure 6 , actin alpha 2 ( ACTA2 ), collagen type I alpha 1 chain ( COL1A1 ), and tissue inhibitor of metalloproteinases 1 ( TIMP1 ) showed a trend toward upregulation in the M+C and PIC+C hydrogels after TGFβ pathway activation.

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