The plasma ammonia levels in BDL animals were also higher (2.4–6.6 fold) than those in their corresponding Sham animals in all three time groups but the 2.4-fold difference for the 4 Week group did not reach statistical significance ( p > 0.05), most likely due to the high variability in the data (Fig. 1 c).
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Bile duct ligation-induced cirrhosis does not alter the blood-brain barrier permeability to sucrose in rats.
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