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Cellular trafficking and fate mapping of cells within the nervous system after in utero hematopoietic cell transplantation.

Commun Biol · 2024 · PMC11621337 · PMID 39638879

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Between these two points, there is a clear trend toward increased CNS chimerism with increasing age, suggesting that engrafted donor cells undergo measurable expansion during this period, despite the decay in peripheral blood chimerism at a rate of 1.85% each month (ANOVA linear trend analysis, p = 0.0005) (Fig. 8h ).

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