Barely Significant
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Association Between Smell Loss, Disease Burden, and Dupilumab Efficacy in Chronic Rhinosinusitis with Nasal Polyps.

Am J Rhinol Allergy · 2025 · PMC11626849 · PMID 39300794

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Looking at Week 52 (SINUS-52 study only), a similar pattern of results was seen except that the difference in magnitude of improvement in RS-VAS with dupilumab between LoS subgroups did not reach statistical significance.

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