Impacts of double biopsy and double vitrification on the clinical outcomes following euploid blastocyst transfer: a systematic review and meta-analysis.

Although some comparisons in our meta-analysis did not reach statistical significance through multivariable regression analyses adjusting for potential confounders, adverse impacts were evident in clinical pregnancy and live birth/ongoing pregnancy rate following ‘double biopsy + double vitrification’ and ‘single biopsy + double vitrification’ ( Figs 2 and 3 ).

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