Increased intrinsic membrane excitability is associated with olivary hypertrophy in spinocerebellar ataxia type 1.

There was similarly lower Calb + neurons in 30-week SCA1-KI mice compared to littermate controls as in 14-week SCA1-KI mice, although this did not reach statistical significance ( P = 0.0658) ( Fig. 2I ). 30-week old animals also showed no difference in total IO cell number ( Fig. 2J ) or mean IO volume ( Fig. 2K ).

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