Amygdala-predominant α-synuclein pathology is associated with exacerbated hippocampal neuron loss in Alzheimer's disease.

The semi-partial Spearman correlation, controlling for age at death, revealed a significant trend of increasing αSyn limbic/brainstem ratio with higher ADNC severity ( Fig. 1A , ρ = 0.51, P < 0.001).

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