Examining the role of common variants in rare neurodevelopmental conditions.

3a ), we saw nominally significant over-transmission of PGS NDC,DDD in 1,567 families not included in the original GWAS (pTDT deviation 0.062, paired t -test P = 0.014).

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This implies limited or no direct genetic effects, whereas the non-transmitted coefficients were highly significant (Fig. 4 and Supplementary Table 10 ).

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