Genomic virulence markers are associated with severe outcomes in patients with Pseudomonas aeruginosa bloodstream infection.

Commun Med (Lond) · 2024 · PMC11634891 · PMID 39663376

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Additionally, ST446 showed a trend toward increased mortality, with an OR of 4.82 (95% CI: 0.92–25.14, p = 0.06) for 7-day mortality and an OR of 3.69 (95% CI: 0.86–15.81, p = 0.08) for 30-day mortality.

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a notable trendno p-value reported

While no specific sequence types were statistically associated with the occurrence of septic shock at the onset of bloodstream infection, a notable trend was observed for ST235 and ST179, both belonging to virulence cluster E, and ST313 distributed in several clusters.

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