We then performed hierarchical clustering analysis using normalized read counts for all 67 selected unique regions and observed perfect separation between MPNST and NF1 groups with a clear trend of hypermethylation and higher variability in plasma from patients with MNPST (Figure 6 ).
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Plasma DNA Methylation-Based Biomarkers for MPNST Detection in Patients With Neurofibromatosis Type 1.
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