Human papillomavirus genotype and cycle threshold value from self-samples and risk of high-grade cervical lesions: A post hoc analysis of a modified stepped-wedge implementation feasibility trial.

Comparing by HPV Ct values, we observed a clear trend of decreased HPV positivity on clinician-collected samples with increasing Ct levels: 80.1% (218/272, 95% CI [75.0%, 84.4%]), 52.5% (114/217, 95% CI [45.9%, 59.1%]), and 24.3% (89/366, 95% CI [20.2%, 29.0%]) for individuals with HPV Ct of below 30, 30 to 35, and above 35, respectively.

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