Moreover, EpoR and the hypoxia-inducible transcription factor (HIF) Hif2 , a major stimulus of EPO, were upregulated in the bone marrow ( Fig 6C ) and kidney ( Fig 6D ), respectively, in mice fed 1.65% Pi diet, although EpoR upregulation did not reach statistical significance.
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Phosphorus-independent role of FGF23 in erythropoiesis and iron homeostasis.
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