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Restoring Compromised Cl<sup>-</sup> in D2 Neurons of a Huntington's Disease Mouse Model Rescues Motor Disability.

J Neurosci · 2024 · PMC11638812 · PMID 39500579

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When KCC2 was overexpressed in D1 MSNs of R6/2 mice, performance on the rotarod appeared to improve generally (Weeks 12–13), although this did not reach statistical significance ( Fig. 6 C , Extended Data Table 6-3 ).

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