A Novel Class of FKBP12 Ligands Rescues Premature Aging Phenotypes Associated with Myotonic Dystrophy Type 1.

Next, we measured the calcium levels and found that the treatment with MP-002 significantly rescued the increased levels in DM1 cells (MP-001 trended towards normalization but did not reach statistical significance), whereas no effect was detected in control cells ( Figure 1 G).

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