In addition, analysis of publicly available data from acute myeloid leukemia (AML) patients showed a trend towards decreased overall survival in adult leukemia cases with higher PLK-1 expression, which extended beyond those with MLL fusions ( Figure 1 D).
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Only Infant <i>MLL</i>-Rearranged Leukemia Is Susceptible to an Inhibition of Polo-like Kinase 1 (PLK-1) by Volasertib.
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