Antifungal Prophylaxis Utilization and the Associated Clinical Outcomes Among Pediatric Patients with Hematological Malignancies or Undergoing Hematopoietic Stem Cell Transplantation.

J Clin Med · 2024 · PMC11642336 · PMID 39685638

Europe PMC DOI

hedged sentences

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

did not reach statistical significancep = 0.074so close (0.05 < p ≤ 0.1)

Although the presence of two or more risk factors for IFI was higher in patients not on antifungal prophylaxis, this difference did not reach statistical significance ( p = 0.074).

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borderline significantno p-value reported

Furthermore, prophylaxis significantly reduced fungal-related mortality and documented IFI, although the reduction in overall mortality was borderline significant (RR, 0.88; 95% CI, 0.74 to 1.06) [ 35 ].

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