The metabolic ratios for M2/4 ( r = 0.40, p = 0.0640) and M5 ( r = 0.40, p = 0.0624) showed a trend toward a positive correlation with patient age, but this was not statistically significant.
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Interindividual variability in CYP3A-mediated venetoclax metabolism in vitro and in vivo in patients with chronic lymphocytic leukemia.
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