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Excess shed mesothelin disrupts pancreatic cancer cell clustering to impair peritoneal colonization.

FASEB J · 2024 · PMC11646052 · PMID 39673668

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Interestingly, both KO+∆591Mu and KO+∆591WT expressed less MUC‐16 on the cell surface than parent or MSLN KO cells, although the trend did not reach statistical significance in the KO+∆591WT line (Figure 3H ).

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