A stacking ensemble machine learning model for evaluating cardiac toxicity of drugs based on in silico biomarkers.

CPT Pharmacometrics Syst Pharmacol · 2024 · PMC11646942 · PMID 39185761

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a positive trendno p-value reported

As the drug concentration increases, the APD‐related biomarkers (panels a and b) generally show a positive trend for high‐ and intermediate‐risk drugs.

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a negative trendno p-value reported

There is a negative trend for low‐risk compounds for loratadine, nitrendipine, and nifedipine.

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