Amyloid-β oligomers increase the binding and internalization of tau oligomers in human synapses.

To determine whether Aβ was associated with tauO pathology in AD synaptosomes, a linear regression analysis was performed, which revealed a positive correlation between Aβ and tauO, though this relationship did not reach statistical significance (slope = 2.33, R 2 = 0.48, F (1, 5) = 4.57, p = 0.09) (Fig. 2 d).

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