The apparent K D D values of 23.7 ± 8.2 μM, 23.5 ± 14.1 μM, and 20.6 ± 13.8 μM, for Y84A, F193A, and Y84A/F193A, respectively, were less than half the apparent WT xArr1 K D D of 52.8 ± 14.6 μM, although these differences did not reach statistical significance under multiple pairwise analysis ( Table 1 ).
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Mechanisms of amphibian arrestin 1 self-association and dynamic distribution in retinal photoreceptors.
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