Increased expression levels of PIEZO1 in visceral adipose tissue in obesity and type 2 diabetes are triggered by mechanical forces and are associated with inflammation.

Since mechanical stretch activates PIEZO1 in caveolae, the expression of CAV1 was analyzed and, although a tendency towards an increase in patients with obesity was detected, differences did not reach statistical significance (Fig. 2 H).

also in 111,027 other papers