Vitamin D binding protein genetic isoforms, serum vitamin D, and cancer risk in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.

PLoS One · 2024 · PMC11661580 · PMID 39705237

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a significant trendno p-value reported

quintile one, with a significant trend test (p-trend = 0.04; Table 2 ).

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marginally significantno p-value reported

Risk of overall cancer was significantly elevated in quintile four for individuals with any Gc-2, with a marginally significant trend (p-trend = 0.06), but the statistical test for a 25(OH)D-Gc isoform interaction was not significant (p-interaction = 0.46; Table 2 ).

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