Association of plasma homocysteine with cognitive impairment in patients with Parkinson's disease.

When Hcy levels were ≥ 10 μmol/L, the odds of PD-MCI also increased by 112% (OR = 2.12, 95% CI: 0.50∼8.97), though this increase did not reach statistical significance. 3.3 Associations between plasma homocysteine levels and cognitive domains or other non-motor symptoms Further analysis using a generalized linear model identified significant associations between plasma Hcy levels and cognitive domains, as well as other non-motor symptom rating scales ( Table 3 ).

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