For the MV3 spheroids, we found a clear trend of decreasing cell invasion with decreasing matrix pore size, going from 2.4 mg/mL collagen to 8 mg/mL collagen and to 30 mg/mL GelMA and finally to 50 mg/mL ( Figure 2 E).
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EMT-related cell-matrix interactions are linked to states of cell unjamming in cancer spheroid invasion.
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