Higher baseline AUQ scores on study Day 1 were associated with greater reduction in AUQ scores following exposure to alcohol cues under PF-5190457 compared with placebo, but the correlation did not reach statistical significance ( r = 0.293, P = 0.13; Supplemental Figure 1 ; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.182331DS1 ).
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A randomized, double-blind, placebo-controlled study of a GHSR blocker in people with alcohol use disorder.
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