SV2A PET shows hippocampal synaptic loss in cognitively unimpaired APOE ε4/ε4 homozygotes.

Alzheimers Dement · 2024 · PMC11667521 · PMID 39475191

Europe PMC DOI

hedged sentence

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

showed a trendP < 0.085so close (0.05 < p ≤ 0.1)

We did not find differences in synaptic density in cortical [ 11 C]UCB‐J SUVR CS , although differences in the medial temporal cortex, parietal cortex, and precuneus showed a trend toward statistical significance ( P < 0.085 for all).

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