Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.

Although the association did not reach statistical significance, the BIN1 variant showed a consistent direction of effect in the AA and HIS subgroups (AA: rs4663105, MAF = 0.41, OR = 1.16, p = 0.0064; HIS: rs4663105, MAF = 0.40, OR = 1.10, p = 0.15).

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