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Co-Inhibition of tGLI1 and GP130 Using FDA-Approved Ketoconazole and Bazedoxifene Is Synergistic Against the Growth and Metastasis of HER2-Enriched and Triple-Negative Breast Cancers.

Cells · 2024 · PMC11674475 · PMID 39768178

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TGLI1 and GP130 protein expressions were found to be significantly elevated in HER2-enriched breast cancer subtypes and trended for TNBC but did not reach statistical significance ( Figure 1 B).

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