Potential Serum HMGB1, HSP90, and S100A9 as Metastasis Predictive Biomarkers for Cancer Patients and Relevant Cytokines: A Pilot Study.

Int J Mol Sci · 2024 · PMC11675498 · PMID 39768997

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showed a trendno p-value reported

Moreover, the candidate DAMPs showed a trend of negative correlation with serum cytokine, for example, IL-15 and IFN-γ, which strongly decreased in metastasis patients.

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highly significantno p-value reported

Surprisingly, the spread of cancer cells in M1 patients exhibited highly significant levels of HMGB1, HSP90, and S100A9 when compared with M0 patients ( Figure 1 ).

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