Optimizing T cell inflamed signature through a combination biomarker approach for predicting immunotherapy response in NSCLC.

Sci Rep · 2024 · PMC11682295 · PMID 39733163

Europe PMC DOI

hedged sentence

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closest p · 1.6× alpha

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boldest claim

The sentences

nearly significantp = 0.08so close (0.05 < p ≤ 0.1)

Associations with the T cell inflamed GEP were positive in all cohorts but only significant in Kim2020 ( p = 0.04; NSCLC), Kim2018 ( p = 0.0042; GC), and Gide2019 ( p = 3.4e-5; melanoma), nearly significant in Hwang2020 ( p = 0.08; NSCLC) likely due to small sample size but not significant in Riaz2017 ( p = 0.22; melanoma) and Hugo2016 ( p = 1; melanoma).

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