Of the 474 patients treated with EGFR inhibitors, patients with heart disease had a higher rate of cardiotoxicities (3.4%) than those with other comorbidities (0.6%), although the differences did not reach statistical significance (P=0.054).
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Targeted therapy‑associated cardiotoxicity in patients with stage‑IV lung cancer with or without cardiac comorbidities.
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0.0540
0.0540