Barely Significant
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ATRX silences Cartpt expression in osteoblastic cells during skeletal development.

J Clin Invest · 2025 · PMC11684799 · PMID 39744954

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showed a trendno p-value reported
Based on micro-CT analysis on these founder mice, Cartpt deletion showed a trend toward to decreased trabecular bone volume in femurs in a dosage-dependent manner (biallelic showed a greater reduction of bone mass compared with monoallelic Cartpt deletion) ( Supplemental Figure 11 ).

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a decreasing trendno p-value reported
an increasing trendno p-value reported
With high efficiency in Cartpt deletion ( Figure 6E ), Rankl showed an increasing trend while Opg expression revealed a decreasing trend in Atrx-cKO BMSCs ( Figure 6, F and G ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.