This approach revealed a significant decrease in the CD3 + T-cell population in the lungs of DM mice as compared with their euglycemic cohort and a nearly significant decrease specifically in CD8 + T-cells ( Fig. 3 C ), consistent with the results of the whole lung bulk-RNA seq experiment.
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Disruption of immune responses by type 1 diabetes exacerbates SARS-CoV-2 mediated lung injury.
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