Barely Significant
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Global Burden, Trends, and Inequalities of Gallbladder and Biliary Tract Cancer, 1990-2021: A Decomposition and Age-Period-Cohort Analysis.

Liver Int · 2025 · PMC11688657 · PMID 39742398

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an increasing trendno p-value reported
Interestingly, all age subgroups of males in high‐middle, middle, and low‐middle SDI regions indicated an increasing trend (Figure 4B ).

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a negative trendno p-value reported
Regarding the period effect, the past 30 years have seen a negative trend globally, except for low and low‐middle SDI regions.

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an overall trendno p-value reported
The average annual percent change (AAPC) was also computed to provide an overall trend estimate from 1990 to 2021.

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a decreasing trendno p-value reported
With the 1917 year as the watershed, the birth cohort effect exhibits a decreasing trend for individuals born in the following periods.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.