Pivotal roles of biglycan and decorin in regulating bone mass, water retention, and bone toughness.

Bone Res · 2025 · PMC11693767 · PMID 39743559

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showed a trendno p-value reported

In comparison to WT mice, the single KO of Dcn or Bgn showed a trend of reduction in mineralized GAGs, while the dKO mice showed a significant reduction.

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a slight trendno p-value reported

Specifically, Bgn HO and Dcn HO mice exhibited a slight trend toward higher ERK phosphorylation levels, which was completely abolished in Bgn HO/ Dcn HT mice (Fig. 7c ).

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