Barely Significant
← all excerpts

uORF-targeting steric block antisense oligonucleotides do not reproducibly increase RNASEH1 expression.

Mol Ther Nucleic Acids · 2025 · PMC11697566 · PMID 39759875

Europe PMCDOI
1
hedged sentence
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

did not reach statistical significancep < 0.05actually significant
Treatment with the PS-2OMe ASO also reduced RNASEH1 protein expression at the 300 nM concentration, although this effect did not reach statistical significance at the p < 0.05 level.

also in 75,281 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.