Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS).

Nat Commun · 2025 · PMC11699139 · PMID 39753538

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showed a trendno p-value reported

We found that CPT1 activity showed a trend of being higher in mitochondria isolated from SOD1 G93A brains at symptomatic stages, contrary to SPC, which showed no significant changes compared to controls (Fig. 3g ).

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