Hypothesized pharmacogenomic and medication influences on tetrahydrocannabinol and cannabidiol metabolism in a cohort of unselected oral cannabis users.

J Cannabis Res · 2025 · PMC11699712 · PMID 39754268

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showed a trendno p-value reported

Additionally, CYP2C9-intermediate and -poor metabolizers (i.e., carriers of the *3 allele) showed a trend toward increased sedation with THC compared to normal metabolizers (Sachse-Seeboth et al. 2009 ).

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