Transgenic rat with ubiquitous expression of angiotensin-(1-7)-producing fusion protein: a new tool to study the role of protective arm of the renin-angiotensin system in the pathophysiology of cardio-renal diseases.

Even though there was a tendency for higher plasma values of ANG 1-7 in female TG7371 transgene-positive rats as compared with female HanSD rats and female TG7371 transgene-negative rats ( p = 0.05012 as compared with female HanSD rats and p = 0.05006 as compared with female TG7371 transgene-negative rats, respectively), evidently the difference did not reach statistical significance level (Fig. 2A ).

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