Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice.

Cell Res · 2025 · PMC11701126 · PMID 39743633

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a clear trendno p-value reported

Additionally, the donor chimerism of old CD150 high HSCs exhibits a clear trend of decline from LT-HSCs through ST-HSCs, MPPs, to PB, while the donor chimerism of old CD150 low HSCs remains relatively stable (Fig. 4e ), supporting a long-term differentiation defect of old CD150 high HSCs.

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.