All hepatic markers including ALB , BSEP , CYP3A4 , MRP2 , and SLC10A1 were much higher expressed than in EM conditions and showed a trend of upregulation between D4 and D9, and, of these, HNF4a and MDR1 were significantly upregulated ( Figure 3 C).
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Accelerated production of human epithelial organoids in a miniaturized spinning bioreactor.
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