Comparison of lateral tail vein and retro-orbital venous sinus as routes of inoculation to study Group B streptococcal systemic infection.

We observed a significant increase in calprotectin expression in GBS-infected mice injected via the RO route compared to naïve controls, and though we observed a 3.6-fold mean increase in GBS-infected mice injected IV, this did not reach statistical significance when compared to the IV-injected naïve controls ( P = 0.2064, Fig. 3B ).

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