Insulin resistance as a mediator in the association between nickel exposure and metabolic dysfunction-associated steatotic liver disease.

Diabetol Metab Syndr · 2025 · PMC11706095 · PMID 39773521

Europe PMC DOI

hedged sentence

0.1160

closest p · 2.3× alpha

0.1160

boldest claim

The sentences

did not reach statistical significanceP = 0.116not close (p > 0.1)

Mediation analysis As shown in Table 4 , the direct impact of nickel exposure on MASLD did not reach statistical significance ( P = 0.116), but the mediated effect was found to be significant ( P = 0.008).

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