The cardiac blood transcriptome predicts de novo onset of atrial fibrillation in heart failure.

Although these results did not reach statistical significance based on the adjusted p -value, ranking based on lowest p-value did show an enrichment of congestive-heart-failure-related genes ( Fig. 7 E). 3.6 Quantitative PCR To validate microarray-based AF predictor gene identification, quantitative PCR (qPCR) was performed on a selection of seven genes; BMP8B, EPS15, LDHAL6A, NEURL1, RNU1–5, SPEG and TRPM5.

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