ACE2 and TMPRSS2 in human kidney tissue and urine extracellular vesicles with age, sex, and COVID-19.

Pflugers Arch · 2025 · PMC11711140 · PMID 39382598

Europe PMC DOI

hedged sentence

0.1180

closest p · 2.4× alpha

0.1180

boldest claim

The sentences

did not reach statistical significancep = 0.118not close (p > 0.1)

However, the overall fit of the model did not reach statistical significance (F(2, 13) = 2.531, p = 0.118), suggesting that disease severity and sex combined do not affect urine ACE2 levels (Fig. 4 i).

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