Prognostic factors in patients with localized and metastatic alveolar rhabdomyosarcoma. A report from two studies and two registries of the Cooperative Weichteilsarkom Studiengruppe CWS.

In patients with metastatic tumors, PAX3 :: FOXO1 and PAX7 :: FOXO1 ‐positive aRMS had significantly worse EFS and OS compared to patients with eRMS in contrast to patients with FN aRMS whose EFS and OS were much better but did not reach statistical significance (5 year EFS 71% vs. 45%, 5 year OS 70%vs. 56%). 4.

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