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NADPH oxidase 2 small molecule inhibitors as a therapeutic strategy in the treatment of Alzheimer’s disease

Alzheimers Dement · 2024 · PMC11713133

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a strong trendno p-value reported
Conclusion Our preliminary findings show a strong trend in amyloid plaque reduction with ongoing CPP11G/H treatment in older‐aged AD mice and improved vascular function.

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a slight trendno p-value reported
OIS‐BOLD results for vascular reactivity studies show a slight trend of improved vascular function over time with CPP11G/H treatment (Fig. 2).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.